2008年 兰州大学，获学士学位;

　　2013年 复旦大学，获博士学位。

　　2014至2019年间， 威斯康星大学麦迪逊分校(University of Wisconsin Madison)

　　加州大学圣地亚哥分校 (University of California San Diego )

　　2019年8月底回国就任中国科学院生物化学与细胞生物学研究所研究员，研究组长。

　　呼吸系统疾病是世界性的重大健康问题。病毒，衰老及空气污染引起的呼吸系统损伤会导致肺功能的持续性下降，并最终导致死亡。肺部特发性疾病如COPD和肺纤维化，目前在临床上还缺乏有效的治疗药物。本实验室主要利用动物模型和人类器官模型作为主要研究对象，结合多种前沿技术手段解码肺再生的调控机制，为理解和治疗肺部相关疾病提供新的思路和方法。

　　1、肺损伤修复的细胞基础和通讯网络

　　肺含有多种组织干细胞类型，在不同组织区域损伤情况下参与肺损伤修复的干细胞类型也不尽相同。我们想通过单细胞测序、谱系示踪等技术手段鉴定参与肺再生的潜在干细胞类型，并解析调控特定肺干细胞功能的调控因子。

　　2、肺再生的细胞通讯网络

　　肺是一个由中胚层和内胚层来源的细胞构成的复杂器官，在肺损伤再生过程中涉及多种细胞的协同作用。我们将通过组学分析结合条件敲除小鼠模型和类器官模型研究肺再生过程中细胞间的相互作用，揭示肺再生的细胞通讯网络。

　　3、肺部疾病发生的分子机制

　　目前对于肺纤维化、COPD等呼吸系统疾病的发病机制目前还不明确，导致缺乏治疗这些疾病的特效药物。因此，我们将借助于肺疾病动物模型和病人样品，研究例如肺纤维化、COPD等疾病的发病机制并根据分子机制提出潜在的成药靶点和新的治疗策略。

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2. Lin X, Chen W, Yang G, Zhang J, Wang H, Liu Z, Xi Y, Ren T, Liu B, Sui P. Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli. J Clin Invest. 134(19):e176828. doi: 10.1172/JCI176828. (2024)
3. Lv Z, Liu Z, Liu K, Lin X, Pu W, Li Y, Zhao H, Xi Y, Sui P, Vaughan AE, Gillich A, Zhou B. Alveolar regeneration by airway secretory-cell-derived p63+ progenitors. Cell Stem Cell. S1934-5909(24)00291-1. doi: 10.1016/j.stem. (2024)
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9. Ma M, Yang W, Cai Z, Wang P, Li H, Mi R, Jiang Y, Xie Z, Sui P, Wu Y, Shen H. SMAD-specific E3 ubiquitin ligase 2 promotes angiogenesis by facilitating PTX3 degradation in MSCs from patients with ankylosing spondylitis. Stem Cells. 39(5):581-599. doi: 10.1002/stem.3332. (2021)
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12. Sui P, Wiesner DL, Xu J, Zhang Y, Lee J, Van Dyken S, Lashua A, Yu C, Klein BS, Locksley RM, Deutsch G, Sun X. Pulmonary neuroendocrine cells amplify allergic asthma responses. Science. 360(6393):eaan8546. doi: 10.1126/science.aan8546. (2018)
13. Branchfield K, Nantie L, Verheyden JM, Sui P, Wienhold MD, Sun X. Pulmonary neuroendocrine cells function as airway sensors to control lung immune response. Science. 351(6274):707-10. doi: 10.1126/science.aad7969. (2016)
14. Herriges JC, Verheyden JM, Zhang Z, Sui P, Zhang Y, Anderson MJ, Swing DA, Zhang Y, Lewandoski M, Sun X. FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung Branching. Dev Cell. 35(3):322-32. doi: 10.1016/j.devcel. (2015)
15. Sui P, Shi J, Gao X, Shen WH, Dong A. H3K36 methylation is involved in promoting rice flowering. Mol Plant. 6(3):975-7. doi: 10.1093/mp/sss152. (2013)
16. Sui P, Jin J, Ye S, Mu C, Gao J, Feng H, Shen WH, Yu Y, Dong A. H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice. Plant J. 70(2):340-7. doi: 10.1111/j.1365-313X. (2012)
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