代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Yange Gu, Lulu Zhang, Jianhua Li, Ensi Ma, Weiwei Hu, Yun Liu, Xiaocheng Du, Feifei Zhang, Tiange Yang, Linyue Bian, Wenfeng Li, Yitian Jin, Yinghua Wang, Zihan Ning, Chune Yu, Dun Li, Jing Zhao, Chenqi Xu, Zhengxin Wang, Guangchuan Wang,Targeting cholesterol esterification sensitizes liver cancer to CD8+ T cell attack by impairing metabolic and redox resilience,Immunity.2026 Jul 3.
Huan Zhu, Xiuxiu Liu, Muxue Tang, Kathy O Lui, Bin Zhou,Lineage tracing from cellular heritage to disease destiny,Nat Genet.2026 Jun 30.
Yuxiao Zheng, Qi Wang, Chen Dong, Qiong Wang, Mingshun Han, Haiqing Zhao, Shuang Wang, Longlong Chen, Xiaoli Zhang, Dan Yang, Jun Xiao, Zhihuan Chew, Zhenfei Xie, Lei Yang, Jinyong Fan, Xin Zheng, Dezhen Tu, Weiyun Li, Lingming Zheng, Lijian Hui, Xiaowu Huang, Jinsong Li, Huiru Tang, Bin Wei, Hongyan Wang,Targeting PID1 generates oxysterols to switch macrophage cell fates for improved antitumor immunity,Nat Cancer.2026 Jun 16.
Shuangfeng Chen, Fan Deng, Bo Peng, Lian Liu, Junxian Wang, Fuquan Jin, Jiefang Xu, Dongwu Lin, Wen Chen, Danyan Zhang, Chunyan Yi, Jia Zhang, Shufen Zhong, Lin Zhu, Yuying Huang, Jichao Yang, Ran Wang, Xiaoyu Sun, Yaguang Zhang, Zhiyang Ling, Liyan Ma, Xing Liu, Bing Sun,Iron drives protease-independent cleavage of gasdermin D in allergic airway diseases,Cell.2026 Jun 26.
Yirui Ai, Shifeng Li, Siqi Liu, Jia Xu, Yunbin Zhang, Siyu Zhou, Zhou Zhou, Jinsong Li & Yiping Li,One-step generation of semi-cloned zebrafish carrying a defined genetic modification,Cell Res.2026 Jun 12.
Mingyang Yin, Tao Liang, Yumeng Zhang, Guangchuan Wang, Wei Yang, Chenqi Xu,Cholesterol metabolism in immune cells: From mechanisms to therapeutic opportunities,Immunity.2026 Jun 9.
Min Liu, Bing Liu, Chen Chen, Yi-Ran Wang, Xiaoyan Li, Yajuan Zhang, Xinyang Liu, Dingpei Zhou, Hong Gao, Yijun Qi, Chen Su, Dong Gao, Yun Zhao, Yan-Jun Liu, Quanlin Li, Weiwei Yang,Compression-induced metabolic adaptation drives confined tumor cell migration and distant metastasis via malate-dependent microtubule reinforcement,Cell Research.2026 May 18.
Lin Shan, Yunsheng Sun, Sarah A Woodson, Ling-Ling Chen,Elucidating structure-function relationships in the mammalian nucleolus,Nat Rev Mol Cell Biol.2026 May 19.
Tongdong Zhang, Lei Fan, Feibai Yao, Ge Li, Guotong Lin, Yi Yang, Fenglin Qian, Chencheng Liu, Qi Tang, Wendi Wang, Chunfang Xu, Xiaoliang Xu, Yu Chang, Wen Yang, Jiangdong Gong, Yutong Wang, Shichao Huang, Renchu Guan, Lin Lin, Qing Jing, Zhaohua Yang, Tingrui Pan, Xin Cheng, Lei Song, Meirong Du, Zhe Luo, An Zeng,Human PSC-derived sinoatrial node-cardiac plexus assembloids model innervation-associated maturation of pacemaker systems,Cell Stem Cell.2026 May 15.
Chaoxiong Wang, Peixuan Zheng, Anhui Wang, Xinrui Fan, Tianxiang Li, Jingjing Hong, Runze Wang, Chunyan Zhang, Chaogui Luo, Weiwei Yang, Dong Gao, Adili Salai, Min Luo, Zhigang Lu, Dianfan Li, Moubin Lin, Jiayin Peng, Guohui Li, Shuo Han, Yun Zhao,CD300ld on pathologically activated neutrophils promotes tumor immune suppression by binding phosphatidylserine on CD8+ T cells,Nat Cancer.2026 May 15.
Yumeng Wang, Luyu Fan, Qianqian Song, Yaning Li, Jiayu Jin, Qiaoyu Zhao, Weijie Gu, Xiangyi Shi, Dianfan Li, Yao Cong, Sheng Wang,Decoding the structure of GPR151 via NELiS,Proc Natl Acad Sci USA.2026 May 05.
Xueming Meng, Luan Li, Cheng Lin, Yun Zhu, Yanyan Feng, Qun Zhao, Nan Zhao, Xuehai Zhou, Yujie Tong, Shanshan Wang, Guoliang Yin, Ruimin Liu, Lihua Zhang, Fei Sun, Xiumin Yan, Xueliang Zhu, Yao Cong,Chaperonin TRiC bridges radial spokes for folding locally translated proteins to sustain mammalian sperm flagellar motility,Mol Cell.2026 Apr 2.
Lin Zhu, Yuying Huang, Bo Peng, Shufeng Zhong, Xiaoyu Zhang, Fuyang Xiao, Dilare Asim, Jieken Pakezhati, Jinquan Ma, Siying Sun, Jiefang Xu, Shipeng Cheng, Liyan Ma, Zhiyang Ling, Chuyan Yi, Dongmei Lu, Junqin Liang, Bing Sun,Acute stress alleviates type 2 lung inflammation by restricting ILC2s through corticosterone-glucocorticoid receptor signaling,Cell Mol Immunol.2026 Apr 2.
Xiuxiu Liu, Wendong Weng, Zhen He, Kuo Liu, Maoying Han, Wenjuan Pu, Bin Zhou,Highly regional generation and heterogeneous differentiation of basal cells in mouse trachea,Cell Discov.2026 Mar 30.
Zhengtao Zhang, Hong Li, Lingli Chen, Tao Lu, Xinyi Shentu, Yuanhua Liu, Zhixuan Tang, Shuyi Ji, Zhixin Qiu, Yining Zou, Hong Wen, Jing Han, Zhengzeng Jiang, Jie Fan, Xinbo Gao, Dianfan Li, Agavni Mesropian, Roser Pinyol, Josep M Llovet, Hui Dong, Yuan Ji, Lijian Hui,Molecular insights into early malignant transition of hepatocellular carcinoma,Cancer Cell.2026 Mar 26.
Xinzhe Tang, Ming-Han Tong,Mechanism and regulation of meiotic double-strand break formation in mammals,Trends Biochem Sci.2026 Mar 17.
Xinxin Rao, Jingwen Wang, Zhibin Qiao, Lei Hong, Mengxue Qiao, Liangwei Ni, Aixia Song, Yun Deng, Xu Zhao, Jin Meng, Xingxing Chen, Yifan Zhou, Jingyan Xue, Yayun Chi, Xinrui Wang, Zhaowei Yu, Qianqian Chen, Congling Xu, Shuang Tang, Jing Hu, Midie Xu, Wei Xu, Zhen Zhang, Yong Zhang, Yanhui Xu, Yi-Zhou Jiang, Jiong Wu, Minhong Shen, Xiaomao Guo, Xiaoli Yu, Fei Xavier Chen,Paired patient-derived organoids reveal transcription factor-driven epigenetic remodeling in breast cancer metastasis,Cell Stem Cell.2026 Mar 16.
Weihao Sun, Hongyu Liu, Pengcheng Pang, Guanyu Ren, Zhuanghui Feng, Lei Wang, Shuguang Piao, Miaoxia He, Haoyu Shen, Jinsong Li, Xin Li, Chenghua Yang, Linhui Wang, Zhiyong Liu,Integrated single-nucleus transcriptomic and chromatin accessibility analysis reveals key molecular basis of human testicular aging,J Mol Cell Biol.2026 Mar 9.
Xinyi Han, Lingwei Ma, Jiahui Dai, Dong Gao, Wei Wan,Organoids revolutionizing precancer research,J Adv Res.2026 Mar 6.
Yi Ni Luo, Yazi Deng, Yu Liang, Wei Wu, Wei Wu, Lu Wang,A de novo H3.2K9me2 deposition pathway establishes heterochromatin for suppressing transposon mobilization during fly somatic development,Nucleic Acids Res.2026 Feb 24.

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