代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Danyan Zhang, Ayiguzhali Abulitipu, Pengcheng Pang, Lei Bai, Lian Liu, Shaliyan Tuerxunmaimaiti, Wen Chen, Shuangfeng Chen, Houkun Lv, Yadong Fu, Qizhen Du, Fuquan Jin, Chunyan Yi, Yangmin Hao, Liyan Ma, Jinsong Li, Zhiyang Ling, Yaguang Zhang, Liang Zhao, Weiguo Fan, Guoli Du, Bing Sun,ECM1 protects against liver steatosis through PCBP1-mediated iron homeostasis,Hepatology.2025 May 15.
Tao Yang, Xiaohu Hu, Fei Cao, Fenglin Yun, Kaiwen Jia, Mingxiang Zhang, Gaohui Kong, Biyu Nie, Yuexing Liu, Haohao Zhang, Xiaoyu Li, Hongyan Gao, Jiantao Shi, Guanxiang Liang, Guohong Hu, Dennis L Kasper, Xinyang Song, Youcun Qian,Targeting symbionts by apolipoprotein L proteins modulates gut immunity,Nature.2025 May 14.
Yu Xu, Haorui Luo, Jiahao Wang, Haifeng Liu, Luonan Chen, Hongbin Ji, Zimu Deng, Xiaolong Liu,CD103+ T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis,Adv Sci (Weinh).2025 May 8.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen,De Novo Reconstruction of 3D Human Facial Images from DNA Sequence,Adv Sci (Weinh).2025 May 7.
Lijun Wang, Qian Ren, Shuqin Chen, Lixiang Lou, Xuye Hu, Wenhui Xing, Jinlong Suo, Jun Sun, Matthew B Greenblatt, Heng Feng, Weiguo Zou,Piezo1 balances the osteogenic-tenogenic plasticity of periosteal progenitor cells through the YAP pathway,Cell Rep.2025 Apr 24.
Jiacheng Guo, Ni Li, Qiuli Liu, Zongyao Hao, Guanghui Zhu, Xuege Wang, Hanling Wang, Qiang Pan, Beitao Xu, Ying Han, Guoying Zhang, Yannan Lian, Wei Zhang, Yongqiang Gu, Naiheng Lin, Xin Zeng, Zige Jin, Weihua Lan, Jun Jiang, Dong Gao, Liang Dong, Huairui Yuan, Chaozhao Liang, Jun Qin,KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy,Cancer Cell.2025 Apr 22.
Mengning Luo, Xinyang Song,Phyto-metabolites on guard: Role of gut microbial deglycosylation,Cell Host Microbe.2025 Apr 9.
Yurun Lu, Dan Liu, Zhongming Liang, Rui Liu, Pei Chen, Yitong Liu, Jiachen Li, Zhanying Feng, Lei M Li, Bin Sheng, Weiping Jia, Luonan Chen, Huating Li, Yong Wang,A pretrained transformer model for decoding individual glucose dynamics from continuous glucose monitoring data,Natl Sci Rev.2025 Feb 8.
Shunrong Ji, Lihua Cao, Jing Gao, Yang Du, Zeng Ye, Xin Lou, Fen Liu, Yehan Zhang, Junfeng Xu, Xiaohan Shi, Huan Wang, Penghao Li, Yikai Li, Hongxu Chen, Zhicheng Yang, Suizhi Gao, Wuhu Zhang, Dan Huang, Shujuan Ni, Miaoyan Wei, Fei Wang, Yan Wang, Tian Ding, Desheng Jing, Guixiong Fan, Zhiyun Gong, Renquan Lu, Yi Qin, Jie Chen, Xiaowu Xu, Pei Wang, Bing Zhang, Li Ding, Ana I Robles, Henry Rodriguez, David K Chang, Ralph H Hruban, Dong Gao, Daming Gao, Gang Jin, Hu Zhou, Jianmin Wu, Xianjun Yu,Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups,Cancer Cell.2025 Apr 1.
Hengwei Jin, Zixin Liu, Jialing Mou, Muxue Tang, Xiuzhen Huang, Kuo Liu, Qianyu Zhang, Kathy O Lui, Bin Zhou,Dual genetic tracing demonstrates the heterogeneous differentiation and function of neuromesodermal progenitors in vivo,Proc Natl Acad Sci U S A.2025 Apr 8.
Xin Feng, Bo-Wen Jiang, Si-Nan Zhai, Chu-Xiao Liu, Hao Wu, Bang-Qi Zhu, Meng-Yuan Wei, Jia Wei, Li Yang, Ling-Ling Chen,Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer disease phenotypes in mouse models,Nat Biotechnol.2025 Mar 31.
Xinyuan Tong, Gen Lin, Hongbin Ji,"Dr. Jekyll and Mr. Hyde": AT2 Cells in Lung Regeneration and Tumor Development,Cancer Res.2025 Mar 24.
Ning Wang, Sijia Lu, Ziyi Cao, Huimin Li, Junting Xu, Qian Zhou, Hanrui Yin, Qiqi Qian, Xianjing Zhang, Mijia Tao, Quanxin Jiang, Peihui Zhou, Liaoyuan Zheng, Liu Han, Hongtao Li, Limin Yin, Yunqing Gu, Xuefeng Dou, Haipeng Sun, Wei Wang, Hai-Long Piao, Fuming Li, Yingjie Xu, Weiwei Yang, Suzhen Chen, Junli Liu,Pyruvate metabolism enzyme DLAT promotes tumorigenesis by suppressing leucine catabolism,Cell Metab.2025 Mar 13.
Xiang-Le Zhang, Hong-Wei Yue, Ya-Jun Liu, Jian-Yang Wang, Heng-Tong Duan, Yin-Hu Liu, Lei-Lei Jiang, Hong-Yu Hu,Designer polyQ fusion proteins sequester USP7/HDM2 for modulating P53 functionality,iScience.2025 Feb 13.
Yong Jiang, Anran Dai, Yuwei Huang, Hua Li, Jian Cui, Haochen Yang, Lu Si, Tao Jiao, Zhengxu Ren, Ziwei Zhang, Si Mou, Hengrui Zhu, Wenhui Guo, Qiang Huang, Yilin Li, Manman Xue, Jingwei Jiang, Fei Wang, Li Li, Qinying Zhong, Kun Wang, Baichuan Liu, Jinjiao Wang, Gaofeng Fan, Jun Guo, Liang Chen, Creg J Workman, Zhirong Shen, Yan Kong, Dario A A Vignali, Chenqi Xu, Haopeng Wan,Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs,Cell.2025 Mar 6.
Li Zhang, Jianshu Wang, Zhidong Tang, Zhen Lin, Ruibao Su, Naijing Hu, Yao Tang, Gaoxiang Ge, Jing Fan, Ming-Han Tong, Yuanchao Xue, Yu Zhou, Hong Cheng,The nuclear exosome co-factor MTR4 shapes the transcriptome for meiotic initiation,Nat Commun.2025 Mar 17.
Pengfei Dai, Yuanqing Tan, Yifeng Luo, Tingting Liu, Yanchao Huang, Yafang Shang, Min Emma Huang, Xiaojing Liu, Senxin Zhang, Yanyan Wang, Qian-Xi Li, Niu Li, Lulu Li, Yining Qin, Junqi Liu, Liu Daisy Liu, Xia Xie, Yanni Cai, Fei Xavier Chen, Xiaoqi Zheng, Leng-Siew Yeap, Jian Wang, Jinchuan Hu, Fei-Long Meng,Transcription-coupled AID deamination damage depends on ELOF1-associated RNA polymerase II,Mol Cell.2025 Feb 26.
Zhen Lin, Bowen Rong, Ruitu Lyu, Yuxuan Zheng, Yao Chen, Junyi Yan, Meixia Wu, Xiaogang Gao, Fuchou Tang, Fei Lan, Ming-Han Tong,SETD1B-mediated broad H3K4me3 controls proper temporal patterns of gene expression critical for spermatid development,Cell Res.2025 Mar 4.
Si-Kun Guo, Jinlong Suo, Youkui Huang, Xubin Yin, Jinghui Wang, Ling Li, Shaokun Sun, Weiguo Zou, Ling-Ling Chen,Therapeutic circRNA aptamer alleviates PKR-associated osteoarthritis,Sci Bull (Beijing).2025 Feb 20.
Yifan Chen, Yifei Zhou, Yaqing Bai, Kaiwen Jia, Hao Zhang, Qingxia Chen, Mengjiao Song, Yumin Dai, Jiantao Shi, Zhengjun Chen, Xiumin Yan, Yidong Shen,Macrophage-derived CTSS drives the age-dependent disruption of the blood-CSF barrier,Neuron.2025 Feb 19.

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