代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Xingdong Guo, Chengsong Yan, Hua Li, Wenmao Huang, Xiaoshan Shi, Min Huang, Yingfang Wang, Weiling Pan, Mingjun Cai, Lunyi Li, Wei Wu, Yibing Bai, Chi Zhang, Zhijun Liu, Xinyan Wang, Xiaohui F Zhang, Chun Tang, Hongda Wang, Wanli Liu, Bo Ouyang, Catherine C Wong, Yi Cao, Chenqi Xu,Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor.,Cell Res2017,27:505-525.
Zhanyu Ding, Zhenglin Fu, Cong Xu, Yifan Wang, Yanxing Wang, Junrui Li, Liangliang Kong, Jinhuan Chen, Na Li, Rongguang Zhang, Yao Cong.,High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx.,Cell Res2017,27:373-385
Lingbo Wang, Minyin Li, Chao Qu1, Wanying Miao, Qi Yin, Jiaoyang Liao, Huateng Cao,Min Huang, Kai Wang, Erwei Zuo, Guangdun Peng, Shuxin Zhang, Guodong Chen, Qing Li, Ke Tang,Qian Yu, Zhoujie Li, Catherine CL Wong, Guoliang Xu, Naihe Jing, Xiang Yu, Jinsong Li.,CRISPR-Cas9-mediated genome editing in one blastomere of two-cell embryos reveals a novel Tet3 function in regulating neocortical development.,Cell Res2017,27:815-829
Qiaoshi Lian, Jun Xu, Shanshan Yan, Min Huang, Honghua Ding, Xiaoyu Sun, Aiwei Bi, Jian Ding, Bing Sun, Meiyu Geng,Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation,Cell Res2017,27:784-800
Shuyi Ji, Linying Zhu, Yimeng Gao, Xiaoran Zhang, Yupeng Yan, Jin Cen, Rongxia Li, Rong Zeng, Lujian Liao, Chunhui Hou, Yawei Gao, Shaorong Gao, Gang Wei，Lijian Hui,Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening,Cell Res2017,27:642-656
Rekha Rai, Chunyi Hu, Cayla Broton,Yong Chen, Ming Lei, Sandy Chang,NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres,Mol Cell2017,65:801-817
Xiang Li,Chuxiao Liu,Wei Xue,Yang Zhang,Shan Jiang,Qingfei Yin,Jia Wei,Runwen Yao,Li Yang,and Lingling Chen.,Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection,Mol Cell2017,67:214-227.
Xu Xiao, Jingjie Tang, Chao Peng, Yan Wang, Lin Fu, Zhiping Qiu, Yue Xiong, Lianfang Yang, Haiwei Cui, Xiaolong He,Lei Yin,Wei Qi,Catherine C.L.Wong,Yun Zhao,Boliang Li, Wenwei Qiu,Baoliang Song,Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.,Mol Cell2017,66:154-162
Lingjuan He,Xiuzhen Huang,Onur Kanisicak,Yi Li,Yue Wang,Yan Li,Wenjuan Pu,Qiaozhen Liu,Hui Zhang,Xueying Tian,Huan Zhao,Xiuxiu Liu,Shaohua Zhang,Yu Nie,Shengshou Hu,Xiang Miao,Qingdong Wang,Fengchao Wang,Ting Chen,Qingbo Xu,Kathy O.Lui,Jeffery D.Molkentin,Bin Zhou.,Preexisting endothelial cells mediate cardiac neovascularization after injury,J Clin Invest2017,127:2968-2981.
Yongjian Wang,Yan Bian,Jie Luo,Ming Lu,Ying Xiong,Shuyuan Guo,Huiyong Yin,Xu Lin,Qin Li,Catherine C.Y. Chang,Tayuan Chang,Boliang Li,and Baoliang Song.,Cholesterol？and？fatty acids regulate cysteine ubiquitylation of ACAT2 through competitive oxidation.,Nat？Cell？Biol.？2017,19:808-819.
Bo O.Zhou,Hua Yu,Rui Yue,Zhiyu Zhao,Jonathan J.Rios,Olaia Naveiras,Sean J. Morrison.,Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF.,Nat Cell Biol2017,19:891-903
Lingjuan He, Yan Li, Yi Li, Wenjuan Pu, Xiuzhen Huang, Xueying Tian, Yue Wang, Hui Zhang, Qiaozhen Liu, Libo Zhang, Huan Zhao, Juan Tang, Hongbin Ji, Dongqing Cai, Zhibo Han, Zhongchao Han, Yu Nie, Shengshou Hu, Qingdong Wang, Ruilin Sun, Jian Fei, Fengchao Wang, Ting Chen, Yan Yan, Hefeng Huang, William T Pu, Bin Zhou.,Enhancing the precision of genetic lineage tracing using dual recombinases.,Nat？Med.2017,23:1488
Lantao Gou,Junyan Kang,Peng Dai,Xin Wang,Feng Li,Shuang Zhao,Man Zhang,Minmin Hua,Yi Lu,Yong Zhu,Zheng Li,Hong Chen,Ligang Wu,Dangsheng Li,Xiangdong Fu,Jinsong Li,Huijuan Shi,and Mofang Liu.,Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis.,Cell2017,169:1090-1104
Yuhang Xing,Runwen Yao,Yang Zhang,Chunjie Guo,Shan Jiang,Guang Xu,Rui Dong,Li Yang,Lingling Chen.,SLERT Regulates DDx21 Rings Associated with Pol I Transcription. (2017),Cell2017,169:664–678.
Li Yang and Lingling Chen.,Enhancing the RNA engineering toolkit.,Science2017,358,996-997.
Ludi Zhang,Lijian Hui,Bioengineering: Bile ducts regenerated.,Nature2017,547:171-172.
Shanshan Yan, Hongbo Shen, Qiaoshi Lian, Wenlong Jin, Ronghua Zhang, Xuan Lin, Wangpeng Gu, Xiaoyu Sun, Guangxun Meng, Zhigang Tian, Zheng W. Chen and Bing Sun,Deficiency of the AIM2-ASC Signal Uncovers the STING-Driven Overreactive Response of Type I IFN and Reciprocal Depression of Protective IFN-γ Immunity in Mycobacterial Infection.,J Immunol.
Jing Yang,Alessandro Piai,Hongbin Shen,James J.Chou.,An Exhaustive Search Algorithm to Aid NMR-Based Structure Determination of Rotationally Symmetric Transmembrane Oligomers.,Sci Rep.7:17373
Andreas Bietz,Hengyu Zhu,Manman Xue,Chenqi Xu,Cholesterol Metabolism in T Cells.,Front Immunol
Zhenzheng Hu,Xiangyi Shi,Bowen Yu,Na Li,Ying Huang,Yongning He,Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor.,Structure

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