代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Lin Fu, Hailong Wu, Steven Y. Cheng, Daming Gao, Lei Zhang, Yun Zhao,Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammal.,eLifee15690
Jun Chen, Shengbao Suo, Patrick. P.L. Tam, Jing-Dong J. Han, Guangdun Peng*, Naihe Jing*.,Using Geo-seq to undertake Low-input RNA-sequencing analysis of cell samples at defined geographical locations to enable mapping of the in situ position of single cells,Nature Protocol1
Peng Zhang, Shuting Wang, Sai Wang, Jing Qiao, Lei zhang, Zhe Zhang Zhengjun Chen,Dual Function of Partitioning-defective 3 in the Regulation of YAP Phosphorylation and Activation.,Cell Discovery2016,2, 16021
Lu Song, Jun Chen, Guangdun Peng, Ke Tang, NaiheJing*.,Dynamic Heterogeneity of Brachyury in Mouse Epiblast Stem Cells Mediates Distinct Respond to Extrinsic BMP Signaling.,J. Biol. Chem.291(29):15212-15225
Seung-Gi Jin, , Zhi-Min Zhang, Thomas？L. Dunwell, Matthew？R. Harter, Xiwei Wu, Jennifer Johnson, Zheng Li, Jiancheng Liu, Piroska？E. Szabó, Qiang Lu, Guo-liang Xu, Jikui Song, Gerd？P. Pfeifer,Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration,Cell Report14(3):493-505
Guangdun Peng, Shengbao Suo, Jun Chen, Weiyang Chen, Chang Liu, Fang Yu, Ran Wang, Shirui Chen, Na Sun, Guizhong Cui, Lu Song, Patrick P. L. Tam, Jing-Dong Jackie Han*, Naihe Jing*.,Spatial Transcriptome for the Molecular Annotation of Lineage Fates and Cell Identity in Mid-Gastrula Mouse Embryo,Developmental Cell36, 1-7
Sujing Yuan, Xianlong Fang, Yanni Xu, Aimin Ni, Xin-Yuan Liu, Liang Chu,An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells,Oncotarget[Epub ahead of print]
Xingxing Xu, Yonghui Tao, Xiaobo Gao, Lei Zhang, Xufang Li, Weiguo Zou, Kangcheng Ruan, Feng Wang, Guo-liang Xu, Ronggui Hu,A CRISPR-based approach for targeted DNA demethylation,Cell Discovery2:16009
Chang-Lin Li1,*, Kai-Cheng Li1,*, Dan Wu1, Yan Chen1, Hao Luo4, Jing-Rong Zhao1, Sa-Shuang Wang4,,Somatosensory neuron types identified by high-coverage,Cell Research26:83-102
Yang Q, Lin J, Liu M, Li R, Tian B, Zhang X, Xu B, Liu M, Zhang X, Li Y, Shi H*, Wu L*,Highly Sensitive Sequencing Reveals Dynamic Modifications and Activities of Small RNAs in Mouse Oocytes and Early Embryos,Science Advances2(6): e1501482
Ningning Niu, Rui Shao, Guang Yan and Weiguo Zou1,Bromodomain and Extra-terminal Proteins (BET) Inhibitors Suppress Chondrocyte Differentiation and Restrain Bone Growth.,J Biol Chem291, 26647-26657
Jun Xiong, Zhuqiang Zhang, Jiayu Chen, Hua Huang, Yali Xu, Xiaojun Ding, Yong Zheng, Ryuichi Nishinakamura, Guo-Liang Xu, Hailin Wang, She Chen, Shaorong Gao, Bing Zhu,Cooperative Action between SALL4A and TET Proteins in Stepwise Oxidation of 5-Methylcytosine,Molecular Cell64(5):913-925
Jing Xu, Pei-xue Li, Jun Wu, Yi-jun Gao, Meng-xin Yin, Ye Lin, Ming Yang, Dong-ping Chen, Hai-peng Sun, Zeng-bo Liu, Xiang-chen Gu, Hong-ling Huang, Li-li Fu, Hui-min Hu, Liang-liang He, Wen-qing Wu, Zhao-liang Fei, Hong-bin Ji, Lei Zhang*, Chang-Lin Mei*,Involvement of the Hippo Pathway in Regeneration and Fibrogenesis after Ischemic Acute Kidney Injury: YAP is the Key Effector.,Clinical Science2016,130:349-363
Lianxin Hu, Jiajun Xu, Meng-Xin Yin, Liguo Zhang, Yi Lu, Wenqing Wu, Zhaoyu Xu, Margaret S. Ho, Guanjun Gao, Yun Zhao, Lei Zhang,Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.,Cell Discovery2016, 2, 15047
Yuan-Qin Yang, Wen-Jie Dong, Xiao-Fei Yin, Yan-Ni xu, Yu Yang, Jiao-Jiao Wang, Su-Jing Yuan, Jing Xiao, Jonathan Howard Delong, Liang Chu, Hai-Neng Xu, Xiu-Mei Zhou, Ru-Wei Wang, Ling Fang, Xin-Yuan Liu, Kang-Jian Zhang,Interferon-related secretome from direct interaction between immune cells and tumor cells is required for upregulation of PD-L1 in tumor cells,Protein Cell7(7):538-543
Shuai Wu, Jinghua Gui, Xiaofei Yin, Qiang Pan, Xinyuan Liu, Liang Chu,Transmembrane domain is crucial to the subcellular localization and function of Myc target 1,J. Cell. Mol. Med.20(3): 471-481
Hongli Hu,Wenwei Zhu,Jun Qin,Min Chen,Liyan Gong,Long Li,Xiangyuan Liu,Yongzhen Tao,Huiyong Yin,Hu Zhou,Lisha Zhou,Dan Ye,Qinghai Ye,Acetylation of PGK1 Promotes Liver Cancer Cell Proliferation and Tumorigenesis,Hepatology
Haineng Xu, Jiasheng Mu, Jing Xiao, Xiangsong Wu, Maolan Li, Tianrun Liu, Xinyuan Liu,CD24 negative lung cancer cells, possessing partial cancer stem cell properties, cannot be considered as cancer stem cells,Am J Cancer Res.6(1): 51-60
Chao Wang, Meng-Xin Yin, Wei Wu, Liang Dong, Shimin Wang, Yi Lu, Jinjin Xu, Wenqing Wu, Sheng Li, and Yun Zhao Lei Zhang,Taiman acts as a co-activator of Yorkie in the Hippo pathway to promote tissue growth and intestinal regeneration.,Cell Discovery2016,2,16006
Shimin Wang, Yi Lu, Meng-Xin Yin, Chao Wang, Wei Wu, Jinhui Li, Wenqing Wu, Ling Ge, Lianxin Hu, Yun Zhao, Lei Zhang,Importin α1 mediates Yorkie nuclear import via N-terminal non-canonical nuclear localization signal.,The Journal of Biological Chemistry2016,291(15):7926-37

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