代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Chuxiao Liu,Sikun Guo,Fang Nan,Yifeng Xu,Li Yang,Lingling Chen,RNA circles with minimized immunogenicity as potent PKR inhibitors,Mol Cell2021 Dec 23.
Yifan Wang,Cong Xu,Yanxing Wang,Qin Hong,Chao Zhang,Zuyang Li,Shiqi Xu,Qinyu Zuo,Caixuan Liu,Zhong Huang,Yao Cong,Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM,Nat Commun2021 Dec 20.
Zhangcheng Chen,Luyu Fan,Huan Wang,Jing Yu,Dengyu Lu,Jianzhong Qi,Fen Nie,Zhipu Luo,Zhen Liu,Jianjun Cheng,Sheng Wang,Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties,Nat Neurosci2021 Dec 9.
Wenjun Yang,Lele Yang,Jianhua Wang,Yuanyuan Zhang,Sheng Li,Qi Yin,Jinlong Suo,Ruimiao Ma,Yuzhen Ye,Hong Cheng,Jinsong Li,Jingyi Hui,Ping Hu,Msi2-mediated MiR7a-1 processing repression promotes myogenesis,J Cachexia Sarcopenia Muscle2021 Dec 8.
Zhixuan Huang,Jing Li,Qingping Xiong,Hao Li,Enduo Wang,Rujuan Liu,Position 34 of tRNA is a discriminative element for m5C38 modification by human DNMT2,Nucleic Acids Res2021 Dec 6.
Hongling Zhang,Yuanyuan Li,Yongjian Ma,Chongping Lai,Qian Yu,Guangyong Shi,Jinsong Li,Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells,Protein Cell2021 Dec 5.
Hao Li,Han Dong,Beisi Xu,Qingping Xiong,Caitao Li,Wenqing Yang,Jing Li,Zhixuan Huang,Qiyu Zeng,Enduo Wang,Rujuan Liu,A dual role of human tRNA methyltransferase hTrmt13 in regulating translation and transcription,EMBO J2021 Dec 1.
Kai Hao,Yawen Chen,Xiumin Yan,Xueliang Zhu,Cilia locally synthesize proteins to sustain their ultrastructure and functions,Nat Commun2021 Nov 30.
Yunqing Gu,Jun Cao,Xinyu Zhang,Hai Gao,Yuyan Wang,Jia Wang,Juan He,Xiaoyi Jiang,Jinlan Zhang,Guanghui Shen,Jie Yang,Xichen Zheng,Gaowei Hu,Yuanfei Zhu,Shujuan Du,Yunkai Zhu,Rong Zhang,Jianqing Xu,Fei Lan,Di Qu,Guoliang Xu,Yun Zhao,Dong Gao,Youhua Xie,Min Luo,Zhigang Lu,Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2,Cell Res2021 Nov 26.
Qing Zhang,Deqiang Yao,Bing Rao,Liyan Jian,Yang Chen,Kexin Hu,Ying Xia,Shaobai Li,Yafeng Shen,An Qin,Jie Zhao,Lu Zhou,Ming Lei,Xiancheng Jiang,Yu Cao,The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3,Nat Commun2021 Nov 25.
Yi Li,Huan Zhu,Qianyu Zhang,Ximeng Han,Zhenqian Zhang,Linghong Shen,Lixin Wang,Kathy O Lui,Ben He,Bin Zhou,Smooth muscle-derived macrophage-like cells contribute to multiple cell lineages in the atherosclerotic plaque,Cell Discov2021 Nov 23.
Shuangshuang Chen,Geng Zong,Qingqing Wu,Huan Yun,Zhenhua Niu,He Zheng,Rong Zeng,Liang Sun,Xu Lin,Associations of plasma glycerophospholipid profile with modifiable lifestyles and incident diabetes in middle-aged and older Chinese,Diabetologia2021 Nov 20.
Haopeng Wang,Xianming Song,Lianjun Shen,Xinxin Wang,Chenqi Xu,Exploiting T cell signaling to optimize engineered T cell therapies,2021 Nov 19.
Shaohua Zhang,Yan Li,Xiuzhen Huang,Kuo Liu,Qingdong Wang,Alex F Chen,Kun Sun,Kathy O Lui,Bin Zhou,Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis,Circulation2021 Nov 19.
Ning Wang,Yifan Wang,Qian Zhao,Xiang Zhang,Chao Peng,Wenjuan Zhang,Yanan Liu,Olivier Vallon,Michael Schroda,Yao Cong,Cuimin Liu,The cryo-EM structure of the chloroplast ClpP complex,Nat Plants2021 Nov 15.
Yiao Jiang,Jiayin Peng,Jiawen Song,Juan He,Man Jiang,Jia Wang,Liya Ma,Yuang Wang,Moubin Lin,Hailong Wu,Zhao Zhang,Dong Gao,Yun Zhao,Loss of Hilnc prevents diet-induced hepatic steatosis through binding of IGF2BP2,Nat Metab2021 Nov 8.
Huan Zhao,Kathy O.Lui,Bin Zhou,Pancreatic beta cell neogenesis: Debates and updates,Cell Metab2021 Nov 2.
Xinxin Zhu,Na Yang,Yu Yang,Feiyang Yuan,Dandan Yu,Yu Zhang,Zhaoqian Shu,Ning Nan,Hong Hu,Xiaoyan Liu,She Chen,Liming Sun,Huayi Wang,Spontaneous necroptosis and autoinflammation are blocked by an inhibitory phosphorylation on MLKL during neonatal development,Cell Res2021 Nov 2.
Shilin Yuan,Guanghong Liao,Menghuan Zhang,Yuanfei Zhu,Weidi Xiao,Kun Wang,Chuanyin Li,Caiwei Jia,Na Sun,Axel Walch,Daming Gao,Ping Xu,Qiang Deng,Jian Zhang,He Wang,Ronggui Hu,Multiomics interrogation into HBV (Hepatitis B virus)-host interaction reveals novel coding potential in human genome, and identifies canonical and non-canonical proteins as host restriction factors against HBV,Cell Discov2021 Nov 2.
Yajuan Zhang,Hua Yu,Jie Zhang,Hong Gao,Siyao Wang,Shuxian Li,Ping Wei,Ji Liang,Guanzhen Yu,Xiongjun Wang,Xinxiang Li,Dawei Li,Weiwei Yang,Cul4A-DDB1-mediated monoubiquitination of phosphoglycerate dehydrogenase promotes colorectal cancer metastasis via increased S-adenosylmethionine,J Clin Invest2021 Nov 1.

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