代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Shilin Yuan,Guanghong Liao,Menghuan Zhang,Yuanfei Zhu,Kun Wang,Weidi Xiao,Caiwei Jia,Minhui Dong,Na Sun,Axel Walch,Ping Xu,Jiming Zhang,Qiang Deng,Ronggui Hu,Translatomic profiling reveals novel self-restricting virus-host interactions during HBV infection,J Hepatol2021 Apr 7.
Shanshan Wang,Xinyu Thomas Tang,Minghui Lin,Jia Yuan,Yi Jacky Peng,Xiujuan Yin,GuoGuo Shang,Gaoxiang Ge,Zhenggang Ren,Bo O Zhou,Perivenous stellate cells are the main source of myofibroblasts and cancer-associated-fibroblasts formed after chronic liver injuries,Hepatology2021 Apr 5.
Yincong Zhang,Xiaona Zhang,Yumin Dai,Mengjiao Song,Yifei Zhou,Jun Zhou,Xiumin Yan,Yidong Shen,The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing,Nat Commun2021 Mar 19.
Lingjuan He,Wenjuan Pu,Xiuxiu Liu,Zhenqian Zhang,Maoying Han,Yi Li,Xiuzhen Huang,Ximeng Han,Yan Li,Kuo Liu,Mengyang Shi,Liang Lai,Ruilin Sun,Qingdong Wang,Yong Ji,Jan S.Tchorz,Bin Zhou,Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair,Science2021 Feb 26.
Guixin Peng,Yong Zhang,Qinqin Wang,Qingrun Li,Hong Xu,Enduo Wang,Xiaolong Zhou,The human tRNA taurine modification enzyme GTPBP3 is an active GTPase linked to mitochondrial diseases,Nucleic Acids Res2021 Feb 22.
Huijie Zhao,Qingxia Chen,Fan Li,Lihong Cui,Lele Xie,Qiongping Huang,Xin Liang,Jun Zhou,Xiumin Yan,Xueliang Zhu,Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly,Nat Commun2021 Feb 24.
Fei Li,Ming Han,Pengfei Dai,Wei Xu,Juan He,Xiaoting Tao,Yang Wu,Xinyuan Tong,Xinyi Xia,Wangxin Guo,Yunjiao Zhou,Yunguang Li,Yiqin Zhu,Xiaoyu Zhang, Zhuang Liu,Rebiguli Aji,Xia Cai,Yutang Li,Di Qu,Yu Chen,Shibo Jiang,Qiao Wang,Hongbin Ji,Youhua Xie,Yihua Sun,Lu Lu,Dong Gao,Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide,Nat Commun2021 Feb 8.
Ximeng Han,Zhenqian,Lingjuan,Huan Zhu,Yan Li,Wenjuan Pu,Maoying Han,Huan Zhao,Kuo Liu,Yi Li,Xiuzhen Huang,Mingjun Zhang,Hengwei Jin,Zan Lv, Juan Tang,Jinjin Wang,Ruilin Sun,Jian Fei, Xueying Tian,Shengzhong Duan,Qingdong Wang,Lixin Wang,Ben He,Bin Zhou,A suite of new Dre-recombinase drivers markedly expands the ability to perform intersection genetic targeting,Cell Stem Cell2021 Feb 9.
Jinhuan Chen,Yifan Wang,Cong Xu,Kaijian Chen,Qiaoyu Zhao,Shutian Wang,Yue Yin,Chao Peng,Zhanyu Ding,Yao Cong,Cryo-EM of mammalian PA28αβ-iCP immunoproteasome reveals a distinct mechanism of proteasome activation by PA28αβ,Nat Commun2021 Feb 2.
Wenjing Li,Tianlong Zhang,Mingliang Sun,Yu Shi,Xiaojie Zhang,Guoliang Xu,Jianping Ding,Molecular mechanism for vitamin C-derived C5-glyceryl-methylcytosine DNA modification catalyzed by algal TET homologue CMD1,Nat Commun2021 Feb 2.
Wei Zheng,Fan Li,Zhanyu Ding,Hao Liu,Lei Zhu,Cong Xu,Jiawei Li,Qi Gao,Yanxing Wang,Zhenglin Fu,Chao Peng,Xiumin Yan,Xueliang Zhu,Yao Cong,Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM,Proc Natl Acad Sci USA2021 Jan 16.
Beibei Wang,Tianlong Zhang,Jun Yin,You Yu,Wenhao Xu,Jianping Ding,Dinshaw J.Pate,Hui Yang,Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in Type VI CRISPR-Cas systems,Mol Cell2021 Jan 21.
Xue Wang,Yuetong Wang,Zhaoyuan Fang,Hua Wang,Jian Zhang,Longfu Zhang,Hsinyi Huang,Zhonglin Jiang,Yujuan Jin,Xiangkun Han,Shenda Hou,Bin Zhou,Feilong Meng,Luonan Chen,Kwok-Kin Wong,Jinfeng Liu,Zhiqi Zhang,Xin Zhang,Haiquan Chen,Yihua Sun,Liang Hu,Hongbin Ji,Targeting HSPA1A in ARID2-deficient lung adenocarcinoma,Natl Sci Rev2021 Jan 30.
Yufei Han,Qian Zhuang,Bo Sun,Wenping Lv,Sheng Wang,Qingjie Xiao,Bin Pang,Youli Zhou,Fuxing Wang,Pengliang Chi,Qisheng Wang,Zhen Li,Lizhe Zhu,Fuping Li,Dong Deng,Yingchih Chiang,Zhenfei Li,Ruobing Ren,Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism,Nat Commun2021 Jan 19.
Xinyuan Tong,Yueqing Chen,Xinsheng Zhu,Yi Ye,Yun Xue,Rui Wang,Yijun Gao,Wenjing Zhang,Weiqiang Gao,Lei Xiao,Haiquan Chen,Peng Zhang,Hongbin Ji,Nanog maintains stemness of Lkb1-deficient lung adenocarcinoma and prevents gastric differentiation,EMBO Mol Med2021 Jan 13.
Weifeng Guo,Shaowu Zhang,Yuehua Feng,Jing Liang,Tao Zeng,Luonan Chen,Network controllability-based algorithm to target personalized driver genes for discovering combinatorial drugs of individual patients,Nucleic Acids Res2021 Jan 12.
Chao Zhang,Yifan Wang,Yuanfei Zhu,Caixuan Liu,Chenjian Gu,Shiqi Xu,Yalei Wang,Yu Zhou,Yanxing Wang,Wenyu Han,Xiaoyu Hong,Yong Yang,Xueyang Zhang,Tingfeng Wang,Cong Xu,Qin Hong,Shutian Wang,Qiaoyu Zhao,Weihua Qiao,Jinkai Zang,Liangliang Kong,Fangfang Wang,Haikun Wang,Di Qu,Dimitri Lavillette,Hong Tang,Qiang Deng,Youhua Xie,Yao Cong,Zhong Huang,Development and structural basis of a two-Mab cocktail for treating SARS-CoV-2 infections,Nat Commun2021 Jan 11.
Luisa Statello, Chunjie Guo,Lingling Chen,Maite Huarte,Gene regulation by long non-coding RNAs and its biological functions,Nat Rev Mol Cell Biol2020 Dec 22.
Siqi Li,Xiang Li,Wei Xue,Lin Zhang,Shi-Meng Cao,Yunni Lei,LiangZhong Yang,Sikun Guo,Jialin Zhang,Xiang Gao,Jia Wei,Jinsong Li,LiYang,Lingling Chen,Screening for functional circular RNAs using the CRISPR-Cas13 system,Nat Methods2020 Dec 7.
Cong Xu,Yanxing Wang,Caixuan Liu,Chao Zhang,Wenyu Han,Xiaoyu Hong,Yifan Wang,Qin Hong,Shutian Wang,Qiaoyu Zhao,Yalei Wang,Yong Yang,Kaijian Chen,Wei Zheng,Liangliang Kong,Fangfang Wang,Qinyu Zuo,Zhong Huang,Yao Cong,Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM,Sci Adv2020 Dec 4.

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