代表性论文与综述--中国科学院分子细胞科学卓越创新中心

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Daisong Wang,Jingqiang Wang,Lanyue Bai,Hong Pan,Hua Feng,Hans Clevers,Yi Arial Zeng,Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors,Cell2020 Mar 19.
Feng Li,Peng Yuan,Ming Rao,Chunhui Jin,Wei Tang,Yefei Rong, Yunping Hu,Fengjuan Zhang,Tao Wei,Qi Yin,Tingbo Liang,Ligang Wu,Jinsong Li,Dangsheng Li,Yingbin Liu,Wenhui Lou,Shuang Zhao,Mofang Liu,piRNA-independent function of PIWIL1 as a co-activator for anaphase promoting complex/cyclosome to drive pancreatic cancer metastasis,Nat Cell Biol2020 Mar 16.
Xing He,Chenqi Xu,PD-1: A Driver or Passenger of T Cell Exhaustion?,Mol Cell2020 Mar 5.
Luyu Fan,Liang Tan,Zhangcheng Chen,Jianzhong Qi,Fen Nie,Zhipu Luo,Jianjun Cheng,Sheng Wang,Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands,Nat Commun2020 Feb 24.
Xueying Tian,Lingjuan He,Kuo Liu,Wenjuan Pu,Huan Zhao,Yan Li,Xiuxiu Liu,Muxue Tang,Ruilin Sun,Jian Fei,Yong Ji,Zengyong Qiao,Kathy O Lui,Bin Zhou,Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation,EMBO J2020 Feb 17.
Binlu Huang,Baoliang Song,Chenqi Xu,Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities,Nat Metab2020 Feb 11.
Min Cong,Yuan Wang,Yang Yang,Cheng Lian,Xueqian Zhuang,Xiaoxun Li,Peiyuan Zhang,Yingjie Liu,Jun Tang,Qifeng Yang,Xue Zhang,Hua Xiong,Ronggui Hu,Guohong Hu,MTSS1 suppresses mammary tumor-initiating cells by enhancing RBCK1-mediated p65 ubiquitination,Nature Cancer2020 Jan 20.
Xiaofeng Zhuo,Jian Wang,Jing Zhang，Leilei Jiang，Hongyu Hu,Junxia Lu,Solid-State NMR Reveals the Structural Transformation of the TDP-43 Amyloidogenic Region upon Fibrillation,J Am Chem Soc2020 Feb 7.
Yao Chen,Ruitu Lyu,Bowen Rong,Yuxuan Zheng,Zhen Lin,Ruofei Dai,Xi Zhang,Nannan Xie,Siqing Wang,Fuchou Tang,Fei Lan,Minghan Tong,Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks,Cell Res2020 Feb 11.
Jingbo Zhou,Yong Wang,Qiyu Zeng,Shixin Meng,Enduo Wang,Xiaolong Zhou,Molecular basis for t6A modification in human mitochondria,Nucleic Acids Res2020 Feb 12.
Xin Wang,Zhitong Li,Yue Yan,Penghui Lin,Wei Tang,Daniele Hasler,Rajyalakshmi Meduri,Ye Li,Minmin Hua,Huitao Qi,Dihang Lin,Huijuan Shi,Jingyi Hui,Jinsong Li,Dangsheng Li,Jianhua Yang,Jinzhong Lin,Gunter Meister,Utz Fischer,Mofang Liu,LARP7-Mediated U6 snRNA Modification Ensures Splicing Fidelity and Spermatogenesis in Mice,Mol Cell2020 Feb 3.
Yaguang Zhang,Xuezhen Li,Zhongguang Luo,Liyan Ma,Songling Zhu,Zhishuo Wang,Jing Wen,Shipeng Cheng,Wangpeng Gu,Qiaoshi Lian,Xinhao Zhao,Weiguo Fan,Zhiyang Ling,Jing Ye,Songguo Zheng,Dangsheng Li,Hongyan Wang,Jie Liu,Bing Sun,ECM1 is an essential factor for the determination of M1 macrophage polarization in IBD in response to LPS stimulation,Proc Natl Acad Sci USA2020 Jan 24.
Xueying Tian,Lingjuan He,Kuo Liu,Wenjuan Pu,Huan Zhao,Yan Li,Xiuxiu Liu,Muxue Tang,Ruilin Sun,Jian Fei,Yong Ji,Zengyong Qiao,Kathy O Lui,Bin Zhou,Generation of a self‐cleaved inducible Cre recombinase for efficient temporal genetic manipulation,EMBO J2020 Jan 14.
Lijun Wang,Xiuling You,Sutada Lotinun,Lingli Zhang,Nan Wu,Weiguo Zou,Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk,Nat Commun2020 Jan 15.
Beibei Wang,Wenhao Xu,Hui Yang,Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex,Cell Res2020 Jan 8.
Juan Tang,Haixiao Wang,Xiuzhen Huang,Fei Li,Huan Zhu,Yan Li,Lingjuan He,Hui Zhang,Wenjuan Pu,Kuo Liu, Huan Zhao,Jacob Fog Bentzon,Ying Yu,Yong Ji,Yu Nie,Xueying Tian,Li Zhang,Dong Gao,Bin Zhou,Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration,Cell Stem Cell2019 Dec 27
Jun Xiao,Weiyun Li,Xin Zheng,Linlin Qi,Hui Wang,Chi Zhang,Xiaopeng Wan,Yuxiao Zheng,Ruiyue Zhong,Xin Zhou,Yao Lu,Zhiqi Li,Ying Qiu,Chang Liu,Fang Zhang,Yanbo Zhang,Xiaoyan Xu,Zhongzhou Yang,Hualan Chen,Qiwei Zhai,Bin Wei,Hongyan Wang,Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection,Immunity2019 Dec 24
Qi Yin,Hongye Wang,Na Li,Yifu Ding,Zhenfei Xie,Lifang Jin,Yan Li,Qiong Wang,Xinyi Liu,Liuqing Xu,Qing Li,Yongjian Ma,Yanbo Cheng,Kai Wang,Cuiqing Zhong,Qian Yu,Wei Tang,Wanjin Chen,Wenjun Yang,Fan Zhang,Chen Ding,Lan Bao,Bin Zhou,Ping Hu,Jinsong Li,Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1,Cell Res2019 Dec 18
Xiaoyu Merlin Zhang,Keliang Wu,Yuxuan Zheng,Han Zhao,Junpeng Gao,Zhenzhen Hou,Meiling Zhang,Jiaoyang Liao,Jingye Zhang,Yuan Gao,Yuanyuan Li,Lin Li, Fuchou Tang,Zijiang Chen,Jinsong Li,In vitro expansion of human sperm through nuclear transfer,Cell Res2019 Dec 19
Peng Dai,Xin Wang,Lantao Gou,Zhitong Li,Ze Wen,Zonggui Chen,Minmin Hua,Ai Zhong,Lingbo Wang,Haiyang Su,Huida Wan,Kun Qian,Lujian Liao,Jinsong Li,Bin Tian,Dangsheng Li,Xiangdong Fu,Huijuan Shi,Yu Zhou,Mofang Liu,A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis,Cell2019 Dec 12

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